In a double-blind crossover study in chronic insomniacs, DSIP shortened NREM sleep latency and reduced nocturnal awakenings. The authors judged the improvement of little clinical significance.
Monti JM et al., Int J Clin Pharmacol Res 1987Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
DSIP5 mg
The deep-sleep peptide, researched for sleep architecture and recovery. Delta Sleep-Inducing Peptide, lyophilized for reconstitution.
Lyophilized peptide · single vial
What it is
DSIP (Delta Sleep-Inducing Peptide) is a nonapeptide first described in the 1970s in sleep neurochemistry research. It appears in the sleep-architecture and neuroendocrine literature, where it was investigated as a possible endogenous sleep factor. Its published human record consists of a handful of small trials in chronic insomnia run in the 1980s and early 1990s.
- Class
- Neuropeptides
- Formula
- DSIP · 5 mg
- Format
- Lyophilized powder
How it works
DSIP, delta sleep-inducing peptide, is a neuropeptide researched for sleep architecture and recovery.
Sleep
Named for delta sleep
DSIP was first isolated for its association with deep delta-wave sleep in early animal studies.
Stress
Linked to the stress axis
Research suggests DSIP interacts with stress hormone regulation, including cortisol, in animal models.
Recovery
Studied for restoration
The peptide is researched for sleep quality and recovery rather than sedation, a distinction models try to separate.
Key benefits
- Sleep research focused on deep sleep and sleep architecture.
- Recovery protocols where overnight restoration is the goal.
- Wind-down plans where calm and consistent rest matter more than stimulation.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Mixed evidence base- Sleep latency, sleep efficiency and nocturnal awakenings in adults with chronic insomnia (small double-blind trials)
- 24-hour sleep-wake behaviour and daytime alertness in severe chronic insomnia
- Sleep architecture and slow-wave sleep in animal models
- Whether an endogenous DSIP-like factor exists at all, an open question in review literature
Human data exist but come from small, mostly single-centre trials run in the 1980s and early 1990s, and their results conflict; no modern randomised trial has replicated them.
Key research findings and references
Key research findings
In a double-blind study of 16 adults with chronic insomnia over three laboratory nights, DSIP gave higher sleep efficiency and shorter sleep latency than placebo. The authors called the effect marginal.
Bes F et al., Neuropsychobiology 1992In 14 middle-aged adults with severe chronic insomnia, DSIP improved night sleep with repeated doses, and daytime alertness and performance rose significantly.
Schneider-Helmert D, Eur Neurol 1987In an open, uncontrolled trial, 7 patients with severe insomnia received a series of 10 injections and sleep was reported normalised in all but one case.
Kaeser HE, Eur Neurol 1984Published study duration
- Double-blind insomnia study: three laboratory nights per condition (Bes et al. 1992).
- Open insomnia trial: a series of 10 injections, with follow-up of 3 to 7 months (Kaeser 1984).
- Severe chronic insomnia study: repeated dosing with 24-hour sleep-wake recording (Schneider-Helmert 1987).
Research endpoints
- Sleep latency
- Sleep efficiency
- Number of nocturnal awakenings
- Total waking time
- Daytime alertness and performance
References
- Monti JM et al., Int J Clin Pharmacol Res 1987. DSIP efficacy on short-term administration to chronic insomniacs
- Bes F et al., Neuropsychobiology 1992. Effects of DSIP on sleep of chronic insomniac patients, a double-blind study
- Schneider-Helmert D, Eur Neurol 1987. Effects of DSIP on 24-hour sleep-wake behaviour in severe chronic insomnia
- Kaeser HE, Eur Neurol 1984. A clinical trial with DSIP
- Kovalzon VM, Strekalova TV, J Neurochem 2006. DSIP, a still unresolved riddle
- Graf MV et al., Neurosci Biobehav Rev 1984. Delta-sleep-inducing peptide (DSIP), a review
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
DSIP5 mg
The deep-sleep peptide, researched for sleep architecture and recovery. Delta Sleep-Inducing Peptide, lyophilized for reconstitution.
Choose your vial
Choose strength
Quantity
1 vial
Add 2 more, save 5%
1 × DSIP · 5 mg€49 / vial
€49
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €201 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
- 1 × DSIP · 5 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
Optional spare suppliesHow To Use The Vials
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Independently lab tested
99%+ purity standard
Identity verified by LC-MS
Batch COA available
Tracked delivery to European Union
Research bundles
Explore research bundles
Curated pairs and blends this compound is studied alongside. Priced live from the catalogue.
Research pairFocus & Calm bundle
Semax + Selank
Two neuropeptides reviewed side by side: one studied for attention and cognition, the other for stress response.
Research handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order DSIP?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
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