In 18 normal men, submaximal doses of a growth hormone releasing peptide plus GHRH stimulated growth hormone release synergistically. The authors read this as evidence of two independent mechanisms.
Bowers CY et al., J Clin Endocrinol Metab 1990Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
5mg CJC-1295 (w/o DAC) + 5mg Ipamorelin5 mg
Lyophilized peptide · single vial
What it is
This blend pairs 5 mg of CJC-1295 without DAC with 5 mg of ipamorelin. The first is a short-acting GRF(1-29) analog of growth hormone releasing hormone; the second is a selective agonist at the ghrelin receptor. The two constituents act on separate pituitary receptors, and both sit in growth hormone axis research.
- Class
- Growth Hormone Secretagogues
- Formula
- 5mg CJC-1295 (w/o DAC) + 5mg Ipamorelin · 5 mg
- Format
- Lyophilized powder
How it works
This blend combines two growth hormone secretagogues studied together because their receptors differ.
CJC-1295
The GHRH side
CJC-1295 without DAC is a modified GHRH analog that signals the pituitary's growth hormone releasing hormone receptor.
Ipamorelin
The ghrelin side
Ipamorelin is a selective ghrelin receptor agonist studied for growth hormone release with minimal off-target activity.
Blend
Two doors, one signal
Because the two compounds act on separate receptors, research often studies them together for a combined secretory response.
Key benefits
- Lyophilized powder, reconstituted for repeatable preparation.
- COA-verified identity and purity, batch by batch.
- Research-use plans built around a compound-specific question.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Mixed evidence base- Whether GHRH-receptor and ghrelin-receptor agonists given together release more growth hormone than either alone
- Duration and shape of the growth hormone pulse produced by each class
- Restoration of the growth hormone and IGF-I axis in older adults (GHRH(1-29) analog trials)
- Selectivity of ipamorelin for growth hormone over ACTH, cortisol and prolactin
No published trial has tested this specific two-peptide combination. The evidence covers each constituent alone, plus older human work pairing a GHRH peptide with a growth hormone releasing peptide.
Key research findings and references
Key research findings
For the GHRH-analog constituent, a randomized placebo-controlled study in 19 adults aged 55 to 71 years ran 16 weeks. Nocturnal growth hormone, IGF-I and IGFBP-3 rose.
Khorram O, Laughlin GA, Yen SS, J Clin Endocrinol Metab 1997For the ipamorelin constituent, a dose-escalation study in healthy male volunteers found dose-proportional kinetics and a terminal half-life of about 2 hours. Growth hormone peaked once, near 0.67 hours.
Gobburu JV et al., Pharm Res 1999In a phase 2 trial of ipamorelin in 114 adults after bowel resection, median time to a first tolerated solid meal was 25.3 hours versus 32.6 hours on placebo. The difference was not significant.
Beck DE, Sweeney WB, McCarter MD, Int J Colorectal Dis 2014Published study duration
- GHRH and growth hormone releasing peptide synergy study: single intravenous boluses with sampling across the first hour (Bowers 1990).
- GHRH(1-29) analog study in adults aged 55 to 71: 16 weeks of nightly injections after a 4-week placebo run-in (Khorram 1997).
- Ipamorelin phase 2 postoperative ileus trial: dosing from postoperative day 1 to day 7 or discharge (NCT00672074).
Research endpoints
- Peak and integrated growth hormone concentrations
- Serum IGF-I and IGFBP-3
- Plasma ACTH, cortisol, prolactin, LH and TSH as selectivity measures
- Terminal half-life and clearance
- Lean body mass and fat mass by DXA
References
- Bowers CY et al., J Clin Endocrinol Metab 1990. GH-releasing peptide acts synergistically with GH-releasing hormone in normal men
- Khorram O, Laughlin GA, Yen SS, J Clin Endocrinol Metab 1997. Long-term [Nle27]GHRH-(1-29)-NH2 in age-advanced men and women
- Jetté L et al., Endocrinology 2005. Modified hGRF(1-29) analogs activate the GRF receptor in rats
- Raun K et al., Eur J Endocrinol 1998. Ipamorelin, the first selective growth hormone secretagogue
- Gobburu JV et al., Pharm Res 1999. PK/PD modelling of ipamorelin in human volunteers
- Beck DE, Sweeney WB, McCarter MD, Int J Colorectal Dis 2014. Ipamorelin for postoperative ileus in bowel resection patients
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
5mg CJC-1295 (w/o DAC) + 5mg Ipamorelin5 mg
Choose your vial
Choose strength
Quantity
1 vial
Add 2 more, save 5%
1 × 5mg CJC-1295 (w/o DAC) + 5mg Ipamorelin · 5 mg + 5 mg€109 / vial
€109
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €141 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
- 1 × 5mg CJC-1295 (w/o DAC) + 5mg Ipamorelin · 5 mg + 5 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
Optional spare suppliesHow To Use The Vials
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Independently lab tested
99%+ purity standard
Identity verified by LC-MS
Batch COA available
Tracked delivery to European Union
Research handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order 5mg CJC-1295 (w/o DAC) + 5mg Ipamorelin?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
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