In Sprague Dawley rats, a tetrasubstituted hGRF(1-29) derivative produced a 4-fold larger 2-hour growth hormone area under the curve than unmodified hGRF(1-29). It also resisted dipeptidyl peptidase-4 in vitro.
Jetté L et al., Endocrinology 2005Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
CJC - No DAC10 mg
Mod GRF 1-29. Short-acting growth hormone releasing analog. Lyophilized powder for reconstitution.
Lyophilized peptide · single vial
What it is
CJC-1295 without DAC, also called Mod GRF 1-29, is a synthetic 29-amino-acid analog of growth hormone releasing hormone. It carries four substitutions on the human GRF(1-29) backbone that slow enzymatic breakdown, but it lacks the albumin-binding DAC linker, so its action stays short. It appears in endocrinology research on the pituitary growth hormone axis.
- Class
- Growth Hormone Secretagogues
- Formula
- CJC - No DAC · 10 mg
- Format
- Lyophilized powder
How it works
CJC-1295 without DAC, also called Mod GRF 1-29, is a short-acting GHRH analog studied for pulsatile growth hormone release.
GHRH
The active core
Mod GRF 1-29 keeps the active first 29 amino acids of GHRH, with four substitutions that resist enzymatic breakdown.
Pulse
Keeps the natural rhythm
Without the DAC extension the peptide clears within about 30 minutes, preserving the pituitary's pulsatile pattern in models.
Pairing
Often studied in pairs
Research frequently combines the short-acting form with a ghrelin receptor secretagogue such as ipamorelin.
Key benefits
- Growth-and-performance research focused on the GH axis and lean mass.
- Recovery and body-composition protocols using short, timed GH pulses.
- Commonly paired with a GHRP for a fuller growth-and-performance plan.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Mixed evidence base- Stimulation of pituitary growth hormone release through the GHRH receptor (in vitro and rodent work)
- Restoration of the growth hormone and IGF-I axis in older adults (small controlled trials of GHRH(1-29) analogs)
- Resistance of modified GRF(1-29) sequences to enzymatic degradation
- Body composition measures such as lean mass and skin thickness in ageing research
No published human trial has tested this exact tetrasubstituted GRF(1-29) sequence. The human data come from small studies of closely related GHRH(1-29) analogs, and the molecule-specific work is preclinical.
Key research findings and references
Key research findings
In a single-blind, randomized, placebo-controlled study, 19 adults aged 55 to 71 years received a GHRH(1-29) analog nightly for 16 weeks. Nocturnal growth hormone, IGF-I and IGFBP-3 rose significantly.
Khorram O, Laughlin GA, Yen SS, J Clin Endocrinol Metab 1997In that same 16-week study, skin thickness increased in both sexes, while lean body mass and insulin sensitivity increased only in the men.
Khorram O, Laughlin GA, Yen SS, J Clin Endocrinol Metab 1997In 10 healthy men aged about 68 years, GHRH(1-29) given twice daily for 14 days raised 24-hour growth hormone and IGF-I. Levels no longer differed significantly from those of healthy young men.
Corpas E et al., J Clin Endocrinol Metab 1992Published study duration
- GHRH(1-29) analog study in adults aged 55 to 71: 16 weeks of nightly injections after a 4-week placebo run-in (Khorram 1997).
- GHRH(1-29) study in healthy older men: two 14-day treatment periods separated by 14 days without treatment (Corpas 1992).
- Rat work on modified hGRF(1-29) analogs: single subcutaneous doses with plasma sampling from 15 minutes to 72 hours (Jetté 2005).
Research endpoints
- Peak and 24-hour integrated growth hormone concentrations
- Growth hormone area under the curve after a single dose
- Serum IGF-I and IGFBP-3
- Lean body mass and fat mass by DXA
- Skin thickness
References
- Jetté L et al., Endocrinology 2005. hGRF(1-29)-albumin bioconjugates activate the GRF receptor in rats
- Khorram O, Laughlin GA, Yen SS, J Clin Endocrinol Metab 1997. Long-term [Nle27]GHRH-(1-29)-NH2 in age-advanced men and women
- Corpas E et al., J Clin Endocrinol Metab 1992. GHRH-(1-29) twice daily in old men
- Teichman SL et al., J Clin Endocrinol Metab 2006. CJC-1295, the albumin-binding version of the same GRF(1-29) backbone, in healthy adults
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
CJC - No DAC10 mg
Mod GRF 1-29. Short-acting growth hormone releasing analog. Lyophilized powder for reconstitution.
Choose your vial
Choose strength
Quantity
1 vial
Add 2 more, save 5%
1 × CJC - No DAC · 10 mg€80 / vial
€80
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €170 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
- 1 × CJC - No DAC · 10 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
Optional spare suppliesHow To Use The Vials
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Independently lab tested
99%+ purity standard
Identity verified by LC-MS
Batch COA available
Tracked delivery to European Union
Research bundles
Explore research bundles
Curated pairs and blends this compound is studied alongside. Priced live from the catalogue.
Single-vial blend5mg CJC-1295 (w/o DAC) + 5mg Ipamorelin
CJC - No DAC + Ipamorelin
- Includes
- CJC - No DAC€80
- Ipamorelin€65
Research handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order CJC - No DAC?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
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