In a 26-week randomised placebo-controlled trial in 412 adults with HIV and abdominal fat accumulation, visceral adipose tissue fell 15.2% in the tesamorelin arm, against a 5.0% rise on placebo.
Falutz J et al., N Engl J Med 2007Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
Tesamorelin10 mg
GHRH analog, studied for visceral fat reduction, premium-grade research peptide. Lyophilized powder for reconstitution.
Lyophilized peptide · single vial
What it is
Tesamorelin is a synthetic 44-amino-acid analogue of human growth hormone-releasing hormone, stabilised by a trans-3-hexenoyl group at the N-terminus. It has been studied mainly in adults with HIV and abdominal fat accumulation. It is one of the few growth hormone axis peptides with completed Phase 3 trials and published long-term data.
- Class
- GLP-1 & Metabolic
- Formula
- Tesamorelin · 10 mg
- Format
- Lyophilized powder
How it works
Tesamorelin is a synthetic GHRH analog studied for its effect on visceral fat in clinical research.
GHRH
Signals the pituitary
Tesamorelin binds the growth hormone releasing hormone receptor, prompting the pituitary's own pulsatile GH release.
Visceral
Studied for visceral fat
Clinical trials have examined tesamorelin for reducing visceral adipose tissue, the deep fat around abdominal organs.
IGF-1
Raises the downstream marker
The resulting growth hormone pulse raises IGF-1, the downstream marker researchers track in these models.
Key benefits
- Body-composition research focused on visceral/abdominal fat.
- GH-axis support as a GHRH analog.
- Often paired with other GH-axis peptides for recovery and lean-mass goals.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Human clinical data- Visceral adipose tissue in adults with HIV and abdominal fat accumulation (Phase 3)
- Hepatic fat fraction and non-alcoholic fatty liver disease in adults with HIV
- IGF-1, triglyceride, and cholesterol responses during dosing
- Re-accumulation of visceral fat after dosing stops
Human evidence is substantial and randomised, but almost all of it comes from adults living with HIV, so findings in other populations remain untested.
Key research findings and references
Key research findings
In a 6-month randomised trial in 50 adults with HIV, visceral fat fell 34 square centimetres in the tesamorelin arm, against an 8 square centimetre rise on placebo.
Stanley TL et al., JAMA 2014In a 12-month randomised trial in 61 adults with HIV and fatty liver, 35% of the tesamorelin arm reached hepatic fat below 5%, versus 4% on placebo.
Stanley TL et al., Lancet HIV 2019Published study duration
- Phase 3 visceral fat trial: 26 weeks (NCT00123253).
- Liver fat trial: 6 months (NCT01263717).
- Fatty liver disease trial: 12 months blinded, followed by a 6-month open-label extension (NCT02196831).
Research endpoints
- Visceral adipose tissue area by computed tomography
- Hepatic fat fraction by magnetic resonance spectroscopy
- IGF-1 concentration
- Triglycerides and total cholesterol to HDL ratio
- Body composition and waist circumference
References
- Falutz J et al., N Engl J Med 2007. Metabolic effects of a growth hormone-releasing factor in patients with HIV
- Falutz J et al., J Clin Endocrinol Metab 2010. Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in HIV-infected patients
- Stanley TL et al., JAMA 2014. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation
- Stanley TL et al., Lancet HIV 2019. Effects of tesamorelin on non-alcoholic fatty liver disease in HIV
- ClinicalTrials.gov NCT00123253. Phase 3 study of TH9507 in patients with HIV-associated lipodystrophy
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
Tesamorelin10 mg
GHRH analog, studied for visceral fat reduction, premium-grade research peptide. Lyophilized powder for reconstitution.
Choose your vial
Choose strength
Quantity
1 vial
Add 2 more, save 5%
1 × Tesamorelin · 10 mg€95 / vial
€95
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €155 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
- 1 × Tesamorelin · 10 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
Optional spare suppliesHow To Use The Vials
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Independently lab tested
99%+ purity standard
Identity verified by LC-MS
Batch COA available
Tracked delivery to European Union
Research bundles
Explore research bundles
Curated pairs and blends this compound is studied alongside. Priced live from the catalogue.
Research pairLean & Glow bundle
Retatrutide + GHK-Cu
Weight research paired with skin research. A triple-receptor peptide studied for weight reduction, next to a copper peptide studied for collagen support.
- Includes
- Retatrutide€99
- GHK-Cu€49
Research handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order Tesamorelin?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
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