In a 13-patient randomized CO2 laser resurfacing study, blinded evaluators found no erythema or wrinkle difference at 12 weeks, though patient-rated skin quality favoured GHK-Cu (p = 0.04).
Miller TR et al., Arch Facial Plast Surg 2006Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
GHK-Cu50 mg
Copper Tripeptide-1. Glycyl-L-Histidyl-L-Lysine copper complex. Lyophilized powder for reconstitution.
What it is
GHK-Cu is the copper(II) complex of glycyl-L-histidyl-L-lysine, a tripeptide found naturally in human plasma, saliva and urine. Its plasma concentration falls with age. It appears in skin biology, wound repair and extracellular matrix research.
- Class
- Beauty & Longevity
- Formula
- GHK-Cu · 50 mg
- Format
- Lyophilized powder
How it works
GHK-Cu is a naturally occurring copper tripeptide researched for skin structure, collagen support and remodelling.
Carries copper ions
GHK binds copper ions and delivers them to cells, a transport role thought to underlie much of its activity.
Studied for matrix support
Research examines GHK-Cu for collagen and glycosaminoglycan synthesis in skin models.
A broad signal
Gene expression studies report that GHK modulates a wide set of genes linked to tissue repair and inflammation.
Key benefits
- Skin research focused on collagen, elasticity, and skin density.
- Recovery-and-repair protocols where tissue remodeling is the goal.
- Often paired with weight-loss research when skin support is also a goal.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Mixed evidence base- Collagen and proteoglycan synthesis in cultured dermal fibroblasts
- Skin recovery and erythema after CO2 laser resurfacing (randomized study)
- Closure of chronic venous stasis ulcers (randomized evaluator-blinded trial)
- Reversal of an emphysema-associated gene expression signature in lung fibroblasts
Most GHK-Cu data are preclinical or in vitro; the few controlled human studies are small, topical and inconsistent, and one wound trial showed no benefit over vehicle.
Key research findings and references
Key research findings
In an 86-patient randomized evaluator-blinded venous stasis ulcer trial, a 0.4% tripeptide copper cream did not reduce ulcer size more than the inert vehicle.
Bishop JB et al., J Vasc Surg 1992Computational screening of an emphysema severity gene signature in 64 lung tissue samples identified GHK, which restored collagen I contraction in fibroblasts from COPD lungs.
Campbell JD et al., Genome Med 2012A 2026 systematic review of GHK-Cu in aesthetic medicine included 20 studies, of which 18 were preclinical and only 2 were randomized controlled trials.
Mokhtar J et al., Aesthet Surg J 2026Published study duration
- CO2 laser resurfacing study: 12-week post-procedure follow-up in 13 patients (Miller 2006).
- Aesthetic medicine systematic review: literature searched from database inception to March 2026 (Mokhtar 2026).
Research endpoints
- Blinded erythema scoring after laser resurfacing
- Investigator-rated wrinkle and overall skin quality
- Patient-reported skin quality questionnaire
- Ulcer surface area change
- Collagen I gel contraction by cultured fibroblasts
References
- Miller TR et al., Arch Facial Plast Surg 2006. Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin
- Bishop JB et al., J Vasc Surg 1992. Randomized evaluator-blinded trial of two wound healing agents for venous stasis ulcers
- Campbell JD et al., Genome Med 2012. A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK
- Pickart L et al., Biomed Res Int 2015. GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration
- Mokhtar J et al., Aesthet Surg J 2026. The regenerative potential of GHK-Cu in aesthetic medicine
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
GHK-Cu50 mg
Copper Tripeptide-1. Glycyl-L-Histidyl-L-Lysine copper complex. Lyophilized powder for reconstitution.
Choose your vial
Add 2 more, save 5%
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €201 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
1 × GHK-Cu · 50 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Research bundles
Explore research bundles
Curated pairs and blends this compound is studied alongside. Priced live from the catalogue.
Research pairLean & Glow bundle
Retatrutide + GHK-Cu
Weight research paired with skin research. A triple-receptor peptide studied for weight reduction, next to a copper peptide studied for collagen support.
- Includes
- Retatrutide· 10 mg€99
- GHK-Cu· 50 mg€49
Single-vial blendGlow · 70 mg
GHK-Cu + TB-500 + BPC-157
Save €43 · 21%Same amount of each compound as the vials listed.
View Bundle
Single-vial blendKlow · 80 mg
GHK-Cu + TB-500 + BPC-157 + KPV
Save €74 · 27%Same amount of each compound as the vials listed.
View BundleResearch handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order GHK-Cu?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
You may also research.
Popular stack. A multi-peptide blend, one vial instead of several.Beauty & LongevityGlowSkin · recovery70 mg€165/ vial1
Beauty & LongevityAHK-CuHair · follicles100 mg€55/ vial1
Beauty & LongevityNAD+Cellular energy€65/ vial1
Most studied. The deepest published literature in its research class.Beauty & LongevityEpithalonPineal · telomeres€55/ vial1