In DSS colitis and CD45RB-high transfer colitis in mice, KPV produced earlier recovery, significantly stronger regain of body weight, and significantly reduced inflammatory infiltrate and colonic myeloperoxidase activity.
Kannengiesser K et al., Inflamm Bowel Dis 2008Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
Klow80 mg
Four peptide regenerative blend: GHK-Cu + TB-500 + BPC-157 + KPV. Lyophilized powder for reconstitution.
Lyophilized peptide · single vial
What it is
Klow is a four-peptide blend of GHK-Cu, TB-500, BPC-157, and KPV in a single lyophilized vial. It adds KPV, a lysine-proline-valine tripeptide derived from alpha-melanocyte-stimulating hormone, to the three-peptide GHK-Cu, TB-500, and BPC-157 combination. Each constituent has its own separate literature, and the blend itself has not been studied.
- Class
- Regenerative Peptides
- Formula
- Klow · 80 mg
- Format
- Lyophilized powder
How it works
Klow combines four regenerative peptides studied across skin, tissue repair and inflammation research.
GHK-Cu
The copper signal
GHK-Cu is a copper tripeptide researched for collagen support and skin remodelling.
Repair pair
BPC-157 plus TB-500
BPC-157 is studied for tissue repair while TB-500 is researched for cell migration, the two classic recovery pathways.
KPV
The inflammation side
KPV adds the anti-inflammatory tripeptide, extending the blend toward gut and inflammatory models.
Key benefits
- Recovery research covering skin, soft tissue, and gut support.
- All-in-one recovery protocols combining four studied peptides in one vial.
- Studied as a broader recovery option than the three-peptide blend.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Preclinical research- Skin remodelling and wound repair (GHK-Cu)
- Dermal and corneal repair in animal models and Phase 2 trials (thymosin beta-4)
- Tendon and ligament healing in rodent injury models (BPC-157)
- Intestinal inflammation in mouse colitis models (KPV)
No published research has examined this four-peptide combination. KPV and BPC-157 evidence is entirely preclinical, GHK-Cu human studies are small, and human trials exist only for full-length thymosin beta-4.
Key research findings and references
Key research findings
In rabbit full-thickness open wounds, topical tripeptide-copper complex produced a significantly smaller mean unhealed wound area than untreated controls at days 7, 14, and 21.
Cangul IT et al., Vet Dermatol 2006In a 56-day Phase 2 trial in 9 patients with severe dry eye, the thymosin beta-4 group showed a 35.1% greater reduction in ocular discomfort and a 59.1% greater reduction in corneal fluorescein staining than vehicle at day 56.
Sosne G et al., Cornea 2015In cultured rat tendon fibroblasts, BPC-157 accelerated outgrowth from tendon explants, increased survival under oxidative stress, and raised migration, with dose-dependent FAK and paxillin phosphorylation.
Chang CH et al., J Appl Physiol 2011Published study duration
- Murine DSS colitis model of KPV: colonic inflammation assessed 8 days after DSS treatment (Dalmasso et al., Gastroenterology 2008).
- Rabbit open-wound study of tripeptide-copper complex: wound margins traced at days 0, 7, 14, and 21 (Cangul et al., Vet Dermatol 2006).
- Phase 2 severe dry eye trial of thymosin beta-4: 28 days of dosing with follow-up through day 56 (NCT01393132).
Research endpoints
- Myeloperoxidase activity and inflammatory infiltrate in colonic tissue
- Unhealed wound area and granulation tissue coverage
- Corneal fluorescein staining and ocular discomfort score
- Tendon fibroblast outgrowth and migration
- Body-weight change during experimental colitis
References
- Kannengiesser K et al., Inflamm Bowel Dis 2008. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease
- Dalmasso G et al., Gastroenterology 2008. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
- Cangul IT et al., Vet Dermatol 2006. Evaluation of the effects of topical tripeptide-copper complex and zinc oxide on open-wound healing in rabbits
- Pickart L and Margolina A, Int J Mol Sci 2018. Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data
- Sosne G et al., Cornea 2015. Thymosin beta-4 significantly improves signs and symptoms of severe dry eye in a phase 2 randomized trial
- Chang CH et al., J Appl Physiol 2011. The promoting effect of pentadecapeptide BPC 157 on tendon healing
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
Klow80 mg
Four peptide regenerative blend: GHK-Cu + TB-500 + BPC-157 + KPV. Lyophilized powder for reconstitution.
Choose your vial
Choose strength
Quantity
1 vial
Add 2 more, save 5%
1 × Klow · 80 mg€199 / vial
€199
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €51 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
- 1 × Klow · 80 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
Optional spare suppliesHow To Use The Vials
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Independently lab tested
99%+ purity standard
Identity verified by LC-MS
Batch COA available
Tracked delivery to European Union
Research bundles
Explore research bundles
Curated pairs and blends this compound is studied alongside. Priced live from the catalogue.
Research pairRecover bundle
BPC-157 + TB-500
The best-known recovery pairing in peptide research. Both compounds are studied for tissue repair, and they are studied together because the mechanisms differ.
Research handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order Klow?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
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