In a rat Achilles tendon-to-bone transection model, BPC-157 groups showed higher Achilles functional index scores and significantly greater load to failure and stiffness than saline controls over 21 days.
Krivic A et al., J Orthop Res 2006Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
Wolverine10 mg
Two peptide regenerative blend: BPC-157 + TB-500, split evenly by weight. Pentadecapeptide and Thymosin Beta-4 fragment. Lyophilized powder for reconstitution.
Lyophilized peptide · single vial
What it is
Wolverine is a two-peptide blend of BPC-157 and TB-500 in a single lyophilized vial. BPC-157 is a 15-amino-acid partial sequence of a protein isolated from human gastric juice. TB-500 is a synthetic peptide related to thymosin beta-4, an actin-sequestering protein released by platelets at sites of injury. The blend itself has not been studied as a combination.
- Class
- Regenerative Peptides
- Formula
- Wolverine · 10 mg
- Format
- Lyophilized powder
How it works
Wolverine combines the two best-known recovery peptides in research, paired because their mechanisms differ.
BPC-157
The repair signal
BPC-157 is a gastric peptide fragment studied for tissue repair in tendon, ligament, muscle and gut models.
TB-500
The cell mover
TB-500 is a synthetic thymosin beta-4 fragment researched for cell migration and tissue flexibility.
Blend
Complementary pathways
The two are studied together because one signals repair while the other moves repair cells toward the site.
Key benefits
- Recovery research covering soft-tissue repair and mobility.
- Training-recovery protocols after heavy load or injury.
- The classic BPC-157 plus TB-500 pairing in a single vial.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Preclinical research- Tendon, ligament, and muscle healing in rodent injury models (BPC-157)
- Dermal wound re-epithelialisation and angiogenesis in animal models (thymosin beta-4)
- Corneal surface repair and severe dry eye in Phase 2 and Phase 3 trials (thymosin beta-4)
- Recovery after acute hamstring strain, a Phase 2 trial now recruiting (BPC-157)
No published study has examined this two-peptide combination. BPC-157 evidence is almost entirely preclinical, and human trials exist only for full-length thymosin beta-4, not for the TB-500 fragment.
Key research findings and references
Key research findings
A rat medial collateral ligament transection study reported consistent functional, biomechanical, and histological improvement with BPC-157 across 90 days of follow-up.
Cerovecki T et al., J Orthop Res 2010In a rat full-thickness wound model, thymosin beta-4 increased re-epithelialisation by 42% at 4 days and by as much as 61% at 7 days compared with saline, with greater wound contraction and collagen deposition.
Malinda KM et al., J Invest Dermatol 1999In a 56-day Phase 2 trial in 9 patients with severe dry eye, the thymosin beta-4 group showed a 35.1% greater reduction in ocular discomfort and a 59.1% greater reduction in corneal fluorescein staining than vehicle at day 56.
Sosne G et al., Cornea 2015Published study duration
- Rat Achilles tendon-to-bone study: outcomes assessed at days 1 to 21 (Krivic et al., J Orthop Res 2006).
- Rat medial collateral ligament study: healing followed for 90 days (Cerovecki et al., J Orthop Res 2010).
- Phase 2 severe dry eye trial of thymosin beta-4: 28 days of dosing with follow-up through day 56 (NCT01393132).
Research endpoints
- Achilles functional index
- Load to failure and stiffness
- Rate of re-epithelialisation and wound contraction
- Collagen fibre organisation and vascular index on histology
- Corneal fluorescein staining
References
- Krivic A et al., J Orthop Res 2006. Achilles detachment in rat and stable gastric pentadecapeptide BPC 157
- Cerovecki T et al., J Orthop Res 2010. Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat
- Vasireddi N et al., HSS J 2025. Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review
- Malinda KM et al., J Invest Dermatol 1999. Thymosin beta-4 accelerates wound healing
- Sosne G et al., Cornea 2015. Thymosin beta-4 significantly improves signs and symptoms of severe dry eye in a phase 2 randomized trial
- Treadwell T et al., Ann N Y Acad Sci 2012. The regenerative peptide thymosin beta-4 accelerates the rate of dermal healing
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
Wolverine10 mg
Two peptide regenerative blend: BPC-157 + TB-500, split evenly by weight. Pentadecapeptide and Thymosin Beta-4 fragment. Lyophilized powder for reconstitution.
Choose your vial
Choose strength
Quantity
1 vial
Add 2 more, save 5%
1 × Wolverine · 10 mg€89 / vial
€89
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €161 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
- 1 × Wolverine · 10 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
Optional spare suppliesHow To Use The Vials
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Independently lab tested
99%+ purity standard
Identity verified by LC-MS
Batch COA available
Tracked delivery to European Union
Research bundles
Explore research bundles
Curated pairs and blends this compound is studied alongside. Priced live from the catalogue.
Research pairRecover bundle
BPC-157 + TB-500
The best-known recovery pairing in peptide research. Both compounds are studied for tissue repair, and they are studied together because the mechanisms differ.
Research handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order Wolverine?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
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