In two randomized, double-blind ascending-dose trials in healthy adults, a single subcutaneous dose raised mean plasma growth hormone 2- to 10-fold for 6 days or more. Mean IGF-I rose 1.5- to 3-fold for 9 to 11 days.
Teichman SL et al., J Clin Endocrinol Metab 2006Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
CJC - With DAC5 mg
Mod GRF 1-29. Long-acting growth hormone releasing analog. Lyophilized powder for reconstitution.
Lyophilized peptide · single vial
What it is
CJC-1295 with DAC is a long-acting analog of growth hormone releasing hormone. It is a tetrasubstituted form of human GRF(1-29) carrying a maleimidopropionamide group, the Drug Affinity Complex, which bonds covalently to cysteine 34 of circulating albumin. It appears in endocrinology research on sustained stimulation of the growth hormone and IGF-I axis.
- Class
- Growth Hormone Secretagogues
- Formula
- CJC - With DAC · 5 mg
- Format
- Lyophilized powder
How it works
CJC-1295 with DAC is a long-acting GHRH analog studied for sustained growth hormone elevation.
GHRH
Signals the pituitary
The peptide is a modified version of growth hormone releasing hormone, binding its receptor on the pituitary.
DAC
Built for duration
The drug affinity complex modification lets the peptide bind albumin, extending its half-life from minutes to days.
Sustained
A longer signal
Research models use the DAC form when the question calls for sustained GH and IGF-1 elevation rather than pulses.
Key benefits
- Growth-and-performance research focused on the GH axis and lean mass.
- Recovery and body-composition protocols using sustained GH support.
- Often researched as the long-acting base of a growth-and-performance plan.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Early human data- Pharmacokinetics and duration of growth hormone and IGF-I elevation in healthy adults
- Whether pulsatile growth hormone secretion is preserved during continuous GHRH receptor stimulation
- Growth restoration in GHRH-deficient animal models
- Serum protein markers of growth hormone and IGF-I action
Human evidence is limited to small early-phase pharmacokinetic and pharmacodynamic studies in healthy volunteers, with no published phase 3 outcome trial.
Key research findings and references
Key research findings
In the same trials the estimated half-life was 5.8 to 8.1 days. After repeat dosing, mean IGF-I stayed above baseline for up to 28 days, and no serious adverse reactions were reported.
Teichman SL et al., J Clin Endocrinol Metab 2006In healthy men aged 20 to 40 years, trough growth hormone was 7.5-fold higher one week after a single injection. Mean growth hormone rose 46% and IGF-I rose 45%, with pulse frequency and amplitude unchanged.
Ionescu M, Frohman LA, J Clin Endocrinol Metab 2006In GHRH knockout mice treated for 5 weeks from 1 week of age, once-daily CJC-1295 produced normal body weight and length. Longer intervals of 48 and 72 hours did not fully normalize growth.
Alba M et al., Am J Physiol Endocrinol Metab 2006Published study duration
- Ascending-dose trials in healthy adults: 28 days and 49 days (Teichman 2006).
- Growth hormone pulsatility study: 12-hour overnight sampling before and one week after a single injection (Ionescu 2006).
- GHRH knockout mouse growth study: 5 weeks of treatment (Alba 2006).
Research endpoints
- Peak growth hormone concentration and growth hormone area under the curve
- Serum IGF-I over time
- Plasma half-life and standard pharmacokinetic parameters
- Growth hormone pulse frequency, amplitude and trough level
- Body weight, body length and femur or tibia length in mice
References
- Teichman SL et al., J Clin Endocrinol Metab 2006. Prolonged stimulation of GH and IGF-I secretion by CJC-1295 in healthy adults
- Ionescu M, Frohman LA, J Clin Endocrinol Metab 2006. Pulsatile GH secretion persists during continuous stimulation by CJC-1295
- Jetté L et al., Endocrinology 2005. Identification of CJC-1295 as a long-lasting GRF analog
- Alba M et al., Am J Physiol Endocrinol Metab 2006. Once-daily CJC-1295 normalizes growth in the GHRH knockout mouse
- Sackmann-Sala L et al., Growth Horm IGF Res 2009. Serum protein profile changes after CJC-1295 in normal adults
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
CJC - With DAC5 mg
Mod GRF 1-29. Long-acting growth hormone releasing analog. Lyophilized powder for reconstitution.
Choose your vial
Choose strength
Quantity
1 vial
Add 2 more, save 5%
1 × CJC - With DAC · 5 mg€125 / vial
€125
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €125 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
- 1 × CJC - With DAC · 5 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
Optional spare suppliesHow To Use The Vials
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Independently lab tested
99%+ purity standard
Identity verified by LC-MS
Batch COA available
Tracked delivery to European Union
Research handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order CJC - With DAC?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
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