In a 4-week randomized double-blind trial in 60 healthy adults, oral glutathione lowered the melanin index more than placebo at 2 of 6 measured sites.
Arjinpathana N and Asawanonda P, J Dermatolog Treat 2012Free shipping over €250 · Tracked, discreet delivery in Europe
premium-grade research peptides
L-Glutathione1500 mg
Lyophilized peptide · single vial
What it is
L-glutathione is a tripeptide of glutamate, cysteine and glycine, and the most abundant intracellular thiol antioxidant in human cells. It appears in redox biology, hepatology and dermatology research, where it is studied in reduced and oxidized forms.
- Class
- Beauty & Longevity
- Formula
- L-Glutathione · 1500 mg
- Format
- Lyophilized powder
How it works
Glutathione is the body's own master antioxidant, a tripeptide studied for its role in oxidative stress and cellular detoxification research.
Antioxidant
The cell's own defense
Glutathione neutralizes reactive oxygen species directly and recycles other antioxidants back to their active forms.
Detox
Central to phase II detox
In the liver, glutathione binds toxins and metabolic byproducts, marking them for removal in study models.
Redox
A marker of cellular stress
The ratio of reduced to oxidized glutathione is widely used in research as a readout of oxidative stress.
Key benefits
- Lyophilized powder, reconstituted for repeatable preparation.
- COA-verified identity and purity, batch by batch.
- Research-use plans built around a compound-specific question.
Laboratory research only. Not for human or veterinary use.
What published research is studying
Early human data- Skin melanin index in healthy adults (randomized placebo-controlled trials)
- Melasma and other hyperpigmentation disorders (systematic reviews of oral, topical and intravenous forms)
- Wrinkle depth, skin elasticity and UV spot counts
- Oral bioavailability, which is limited by breakdown in the gut
Several small randomized human trials exist, mostly in dermatology and running 4 to 12 weeks, but systematic reviews still describe the pigmentation evidence as inconclusive.
Key research findings and references
Key research findings
In a 12-week three-arm randomized trial in healthy women, reduced and oxidized glutathione both tended to lower melanin index, and wrinkle reduction reached significance at some sites.
Weschawalit S et al., Clin Cosmet Investig Dermatol 2017A systematic review of 4 clinical studies concluded that the skin-lightening evidence for glutathione remains inconclusive, because of study quality and inconsistent findings.
Dilokthornsakul W et al., J Cosmet Dermatol 2019A 2025 systematic review counted 5 randomized trials of oral glutathione reporting melanin index reductions versus placebo, while the one intravenous placebo-controlled study showed no significant difference.
Sarkar R et al., Int J Dermatol 2025Published study duration
- Oral glutathione whitening trial: 4 weeks in 60 participants (Arjinpathana 2012).
- Reduced and oxidized glutathione trial: 12 weeks, with measurements at each visit (Weschawalit 2017).
Research endpoints
- Skin melanin index by reflectance measurement
- UV spot count on standardized facial imaging
- Wrinkle depth and skin elasticity
- Colorimetric L* value
- Safety laboratory panels and adverse events
References
- Arjinpathana N and Asawanonda P, J Dermatolog Treat 2012. Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study
- Weschawalit S et al., Clin Cosmet Investig Dermatol 2017. Glutathione and its antiaging and antimelanogenic effects
- Dilokthornsakul W et al., J Cosmet Dermatol 2019. The clinical effect of glutathione on skin color and other related skin conditions: a systematic review
- Sarkar R et al., Int J Dermatol 2025. Glutathione as a skin-lightening agent and in melasma: a systematic review
Summaries of published research, for context only. Research use only. Not for human or veterinary use.
premium-grade research peptides
L-Glutathione1500 mg
Choose your vial
Choose strength
Quantity
1 vial
Add 2 more, save 5%
1 × L-Glutathione · 1500 mg€105 / vial
€105
Free1 × 3 ml bacteriostatic water · 10 × 0.5 ml syringes · 10 × alcohol swabs · uu.life research handling card
- €145 to free shipping
- Ships in 1-2 business days
- Discreet EU
What you get
- 1 × L-Glutathione · 1500 mg
Medical supply kitFreeOne kit with every vial1 × 3 ml bacteriostatic water10 × 0.5 ml syringes10 × alcohol swabs- uu.life research handling card
One supply kit ships with every vial: the counts above follow the quantity.
Optional spare suppliesHow To Use The Vials
The standard supplies above ship free with every vial. Add extras only if the research plan needs more.
Independently lab tested
99%+ purity standard
Identity verified by LC-MS
Batch COA available
Tracked delivery to European Union
Research bundles
Explore research bundles
Curated pairs and blends this compound is studied alongside. Priced live from the catalogue.
Research pairLongevity bundle
NAD+ + Epithalon
Cellular energy research next to aging-model research. Two of the most cited longevity compounds, in one order.
Research handling
Full handling guide- 01
Lyophilized, sealed, batch-numbered
Each vial ships as a freeze-dried powder under an inert seal, tied to the batch on its Certificate of Analysis.
- 02
Store cold and dark
Unopened vials are kept refrigerated at 2-8°C away from light. Reconstituted material is stored refrigerated and used within the window the research plan defines.
- 03
Reconstitute with bacteriostatic water
The included bacteriostatic water is added slowly down the vial wall and the vial is swirled, never shaken.
- 04
Research use only
Supplied for laboratory research. Not for human or veterinary use. Handle with the personal protective equipment the laboratory requires.
Before you order
What ships in the box?
The vials selected, plus a free supply kit with every vial: one 3 ml bacteriostatic water, ten 0.5 ml syringes and ten alcohol swabs per vial, and the uu.life research handling card.
How does volume pricing work?
The price per vial depends on how many vials of the same strength are on the line. 3-4 vials take 5% off, 5 or more take 10% off. The discount is applied automatically and shows on the product page, in the cart and at checkout.
Is every batch tested?
Yes. Every batch is tested by an independent laboratory for identity and purity, and the Certificate of Analysis is linked from this page and the lab-testing library.
How fast is delivery?
Orders are typically dispatched within 1-2 business days and arrive across most of Europe in 3-5 business days, tracked, in discreet packaging. Orders over €250 ship free, and Shipping Protection can be added at checkout.
Is this for human use?
No. Every product is sold for laboratory research only and is not for human or veterinary use.
Ready to order L-Glutathione?
Choose a strength and quantity above. Volume pricing applies automatically.
Quality you can trace.
Batch-tested purity
Every vial ships with a Certificate of Analysis from an independent third-party lab. No exceptions.
Fast shipping
Orders are typically dispatched within 1-2 business days. Most European deliveries arrive in 3-5 business days.
Replacement guarantee
Arrived damaged? Send photos and the order number and a replacement is arranged.
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